De-esterification of cephalosporin para-nitrobenzyl esters by microbial enzymes.
- 1 January 1976
- journal article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 29 (2) , 121-124
- https://doi.org/10.7164/antibiotics.29.121
Abstract
Bacteria and actinomycetes were screened for esterase enzymes capable of removing the para-nitrobenzyl ester from cephalosporins. An esterase preparation from Bacillus subtilis was used to prepare cephalexin and 7-ADCA from the corresponding para-nitrobenzyl esters.Keywords
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