Hemoglobin Bart's Levels in Umbilical Cord Blood: Failure as a Method for Distinguishing Mild from Severe α-Thalassemia Trait in the Chinese
- 1 January 1978
- journal article
- research article
- Published by Taylor & Francis in Hemoglobin
- Vol. 2 (4) , 389-392
- https://doi.org/10.3109/03630267809005348
Abstract
There are 4 common varieties of .alpha.-thalassemia, namely, Hb Bart''s (.gamma.4) hydrops fatalis syndrome, Hb H disease, ''severe'' heterozygous .alpha.-thalassemia or .alpha.-thal-1 trait and ''mild'' heterozygous .alpha.-thalassemia or .alpha.-thal-2 trait and a new form resulting from the deletion of 4, 3, 2 and 1, respectively, of the .alpha.-globin structural genes. The cord blood of 26 newborn Chinese children with 1 HbH parent and 1 normal parent were examined. The concentration of Hb Bart''s was not useful in differentiating the .alpha.-thal-1 from the .alpha.-thal-2 trait.This publication has 8 references indexed in Scilit:
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