MITOTIC AND WOUND HEALING ACTIVITIES OF THE CORNEAL EPITHELIUM IN THIOURACIL TREATED AND THYROIDECTOMIZED RATS

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Abstract
The post-traumatic cell movements in the healing of small wounds in the corneal epithelium are not delayed in thiouracil treated rats. With the use of the colchicine technique it was found that both the entrance into mitosis and the speed of the mitotic cycle is reduced in thiouracil treated rats. Rats, in whom thyroidectomy had been performed surgically, showed the same retardation of mitotic activity as the rats treated with thiouracil.