INTRAARTERIAL CHEMOTHERAPY OF HEAD AND NECK TUMORS

  • 1 March 1986
    • journal article
    • research article
    • Vol. 7  (2) , 343-348
Abstract
Forty-one patients with advanced recurrent or untreated head and neck tumors were treated with intraarterial short-term (1-1 1/2 hr) infusion of cisplatin into the external carotid artery, achieving an immediate tumor response rate of 29.3%. Tumor extent within or beyond the territory of a single external carotid artery was the only significant factor identified affecting the tumor response rate (57.1% vs. 14.8%). Treatment with intraarterial chemotherapy using superselective catheterization before irradiation or surgery is beneficial in some patients.