Treatment of Comorbid Generalized Anxiety in a Recently Detoxified Alcoholic Population with a Selective Serotonergic Drug (Buspirone)
- 1 February 1992
- journal article
- editorial
- Published by Wolters Kluwer Health in Journal of Clinical Psychopharmacology
- Vol. 12 (1) , 19???26
- https://doi.org/10.1097/00004714-199202000-00004
Abstract
Recent literature has addressed a common dyad: alcoholism and anxiety. Both disorders have been interdigitated with the brain amine serotonin. We investigated 51 dually diagnosed patients (generalized anxiety/alcohol abuse: dependence) in a randomized, double-blind, placebo-controlled trial of the serotonin partial agonist buspirone. Buspirone was superior to placebo as an anxiolytic, was well tolerated, and was associated with both a reduction in the number of days desiring alcohol and an overall clinical global improvement.Keywords
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