Vaccination granulomas and aluminium allergy: course and prognostic factors

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Abstract
21 children who had cutaneous granulomas following immunization with a vaccine containing aluminium hydroxide, and who had positive patch tests to aqueous aluminium chloride and/or to a Finn Chamber, were Followed for I to 8 years During the period of observation, the symptoms cleared in 5 children. Improved in 11, and remained unchanged in 5. The course of the granulomas could ran he correlated with sex or atopy. nor with intensity of she initial aluminium patch test. 4 children were patch tested again with aluminium.