External anions relieve DIDS inhibition of SO4 efflux from placental membrane vesicles
- 1 October 1986
- journal article
- research article
- Published by Portland Press Ltd. in Bioscience Reports
- Vol. 6 (10) , 889-894
- https://doi.org/10.1007/bf01116242
Abstract
Sulphate efflux from human placental microvillus membrane vesicles was inhibited by external DIDS (KI≅10−6 M). This inhibition was partially reversed on addition of the translocated substrates sulphate or selenate to the external medium: selenite which is not translocated does not protect against DIDS inhibition. These findings show that the mechanism responsible for sulphate efflux can be modified by substrate in the external medium.Keywords
This publication has 9 references indexed in Scilit:
- Sulphate transport into vesicles prepared from human placental brush border membranes: inhibition by trace element oxides.The Journal of Physiology, 1986
- Human placental sulphate transport: studies on chorionic trophoblast brush border membrane vesicles.The Journal of Physiology, 1986
- Sulphate transport in human placental brush-border membrane vesicles: competitive inhibition by selenateBiochimica et Biophysica Acta (BBA) - Biomembranes, 1986
- Active Absorption of Selenate by Rat IleumJournal of Nutrition, 1985
- Sulfate transport in brush border membrane vesicles prepared from human placental syncytiotrophoblastBiochemical and Biophysical Research Communications, 1984
- L‐proline transport by brush border membrane vesicles prepared from human placenta.The Journal of Physiology, 1981
- The use of ion-exchange resins for studying ion transport in biological systemsAnalytical Biochemistry, 1976
- Preparation of human placental villous surface membraneNature, 1974