An Unusual Ocular Complication after Anesthesia

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Abstract
This report describes for the 1st time the occurrence of acute epithelial edema of the cornea and marked decrease in visual acuity after general anesthesia in a patient with previously undetected endothelial dystrophy of the cornea. The edema probably resulted from cytotoxic effects of the antineoplastic drug melphalan, although the condition, once initiated could have been exacerbated by anesthesia-related factors and prolonged closure of the eyes.

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