PLEUROMUTILINS FERMENTATION, STRUCTURE AND BIOSYNTHESIS
- 1 January 1976
- journal article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 29 (2) , 125-131
- https://doi.org/10.7164/antibiotics.29.125
Abstract
Derivatives of pleuromutilin, formed during the fermentation of pleuromutilin, were isolated and their structure determined. 14-Acetyl-mutilin and mutilin as well as different unsaturated fatty acid esters of pleuromutilin were identified. The proportion of each derivative formed depends to a considerable degree on the conditions of the fermentation process. The possible biosynthetic pathways are shown.Keywords
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