The steric effect of a trifluoromethyl group.
- 1 January 1991
- journal article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 39 (1) , 233-235
- https://doi.org/10.1248/cpb.39.233
Abstract
In the study of ene reaction of trifluoromethyl ketones, a trifluoromethyl group was found to behave as a much larger substituent than commonly believed. Similar results were obtained in the dehydration of trifluoromethyl homoallyl alcohols.Keywords
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