Screening of Antifungal Antibiotics According to Activities Inducing Morphological Abnormalities
- 9 September 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in Agricultural and Biological Chemistry
- Vol. 47 (9) , 2061-2069
- https://doi.org/10.1080/00021369.1983.10865911
Abstract
Activities of various known antifungal antibiotics known to induce morphological abnormalities of fungi and yeasts were examined. The observations seemed to provide a standard for detecting new antifungal antibiotics with a selective mode of action. Three new antibiotics, AC549, ATS 1287 (leptomycin) and AM630 (fosfazinomycin), were found according to their activities to induce characteristic morphological changes of test organisms. AC549 seemed to be a compound related to gougeroxymycin.This publication has 0 references indexed in Scilit: