OXIDATION OF PARA-AMINOPHENOL CATALYZED BY HORSERADISH-PEROXIDASE AND PROSTAGLANDIN SYNTHASE
- 1 January 1983
- journal article
- research article
- Vol. 23 (2) , 461-466
Abstract
P-Aminophenol [a nephrotoxic agent] oxidation is catalyzed by horseradish peroxidase. ESR spectroscopy demonstrates the formation of the p-aminophenoxy free radical, the one-electron oxidation product of p-aminophenol. The same radical is formed by alkaline autoxiation of this compound. The ultimate products of p-aminophenol oxidation are mainly polymeric; however, indophenol was isolated in low yield. Oxidation of p-aminophenol is also catalyzed by the hydroperoxidase activity of prostaglandin synthase, using ram seminal microsomal preparations as the enzyme source.This publication has 17 references indexed in Scilit:
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