Experimental immunization of sows with inactivated transmissible gastroenteritis (TGE) virus.
- 1 April 1971
- journal article
- Vol. 35 (2) , 99-102
Abstract
Four sows were immunized with inactivated TGE virus. The virus was either propagated in pig kidney cell cultures, or obtained from the intestines of experimentally infected gnotobiotic pigs, and inactivated by treatment with beta-propiolactone. The inactivated virus preparations were administered to sows by intramammary inoculation. Two sows received two inoculations; the other two sows received three inoculations of inactivated virus. The antibody responses in the serum and milk were determined and piglets nursing the sows were experimentally challenged with virulent TGE virus. Three inoculations of the virus preparation stimulated much higher levels of serum and milk antibody than did two inoculations. A schedule of three inoculations of sows with inactivated TGE virus was effective in stimulating protection against TGE for piglets nursing these sows.This publication has 3 references indexed in Scilit:
- Experimental immunisation of sows against transmissible gastroenteritis. I. Immunisation with a bacteria-free suspension of transmissible gastroenteritis virus prepared from the intestines of infected pigsPublished by Wiley ,1970
- Experimental immunization of sows with cell-cultured TGE virus.1970
- A study of procine enteroviruses isolated from swine in the Toronto area. I. Isolation and serological grouping of viruses.1966