Radiosensitivity and Chromosome Numbers in Strain L Mouse Cells in Tissue Culture

1 September 1961

journal article
research article
Published by JSTOR in Radiation Research

Vol. 15 (3) , 400-+
https://doi.org/10.2307/3571245

Abstract

The radiosensitivity of the ability of strain L mouse cells to form macroscopic colonies is independent of chromosome number in cell lines with mean chromosome numbers between 53 and 109 chromosomes. The radiosensitivity of L-cells is relatively low in comparison with values reported for other mammalian cell lines. A table of Do values, representing the dose to give 37% survival on the exponential portion of the survival curve, is presented. The effect of heteroploidy on the radiosensitivity of mammalian cells is discussed briefly.

Keywords

This publication has 13 references indexed in Scilit:

GENETICS OF HUMAN CELL LINES
The Journal of Experimental Medicine, 1960
Effect of irradiation on cell division and nucleic acid synthesis in strain U-12 fibroblasts
Biochimica et Biophysica Acta, 1960
Some properties of radiation resistant derivatives of L strain mouse cells
Experimental Cell Research, 1960
Radiation resistant derivatives of L strain mouse cells
Experimental Cell Research, 1960
SOME APPLICATIONS OF TISSUE CULTURE METHODS TO RADIATION RESEARCH
1959
GENETICS OF SOMATIC MAMMALIAN CELLS
The Journal of Experimental Medicine, 1958
Mammalian Chromosomes in Vitro. IX. On Genetic Polymorphism in Cell Populations2
JNCI Journal of the National Cancer Institute, 1958
ACTION OF X-RAYS ON MAMMALIAN CELLS
The Journal of Experimental Medicine, 1957
AN INFLUENCE OF PLOIDY ON THE TIME OF EXPRESSION OF DOMINANT LETHAL MUTATIONS IN HABROBRACON
Genetics, 1956
ACTION OF X-RAYS ON MAMMALIAN CELLS
The Journal of Experimental Medicine, 1956