Ophirapstanol Trisulfate, a New Biologically Active Steroid Sulfate from the Deep Water Marine Sponge Topsentia ophiraphidites
- 1 December 1994
- journal article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 57 (12) , 1751-1754
- https://doi.org/10.1021/np50114a024
Abstract
Ophirapstanol trisulfate [1], a new steroid trisulfate related to sokotrasterol trisulfate was isolated from a deep water marine sponge Topsentia ophiraphidites. Compound 1 exhibited significant inhibition in the guanosine diphosphate/G-protein RAS exchange assay. The structure elucidation of 1 and ophirapstanol [2] by nmr spectroscopy is described.Keywords
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