p53 from pathway to therapy
Open Access
- 16 January 2004
- journal article
- Published by Oxford University Press (OUP) in Carcinogenesis: Integrative Cancer Research
- Vol. 25 (7) , 1077-1081
- https://doi.org/10.1093/carcin/bgh186
Abstract
In the 25 years since its first description the p53 protein has been shown to play a key role in both tumour suppression and aging. New discoveries about the function and control of p53 continue to emerge every month and attempts to exploit the system to develop better therapeutics and diagnostics are beginning to be successful in the clinic (1,2).Keywords
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