Heterogenetic Hemagglutinins in Man Following Therapeutic Injections of Immune Sera Produced in Rabbits

Open Access
Publisher Website
Google Scholar
Abstract
The development of non-specific hemagglutinins following the injection of horse serum, and particularly in cases of serum sickness, has been carefully studied by several observers (1–9). Although a definite and generally accepted theory has not yet been established, it seems likely that the phenomenon is due to a distinct antigen, believed to exist in the sera of horses as well as in the red cells of various animal species (horse, sheep, ox, rabbit). These are some of the animals whose blood is agglutinated by the serum from patients with serum sickness. Moreover, according to absorption experiments, the antigen is present in the serum and tissues of some of these animals. Because of its distribution among several species of animals and in accordance with the definition given by Friedberger and Schiff (10), this antigen may be called a heterogenetic one.2

This publication has 0 references indexed in Scilit: