A frequency-duration index (FDI) for the evaluation of ambulatory recordings of gastro-oesophageal reflux

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Abstract
Oesophageal pH monitoring has been undertaken in 20 symptomatic patients and 20 normal subjects for periods of 24 hours at work and in the home using a pH sensitive radiotelemetry capsule and a portable receiving system. There was no correlation between symptoms and endoscopic findings in symptomatic patients. The number and duration of reflux episodes was greater in symptomatic patients than normal subjects during 24 hour ambulatory study (P < 0·002). A frequency-duration index for the evaluation of recordings is described which was significantly greater in symptomatic patients than in normal subjects during both day (P < 0·002) and night (P < 0·008) periods of recording. Discrimination between the two groups was more clearly seen using the frequency-duration index compared to either the frequency of reflux episodes or the cumulative duration of acid reflux.
Funding Information
  • Department of Medical Electronics, St Bartholomews Hospital, London, for technical advice, the Special Trustees, Nottingham Hospitals