Use of in vitro human metabolism studies in drug development
- 1 December 1994
- journal article
- editorial
- Published by Elsevier in Biochemical Pharmacology
- Vol. 48 (12) , 2147-2156
- https://doi.org/10.1016/0006-2952(94)00312-2
Abstract
No abstract availableKeywords
This publication has 64 references indexed in Scilit:
- Use of human hepatocyte cultures for drug metabolism studiesToxicology, 1993
- Validation and use of cloned, expressed human drug-metabolizing enzymes in heterologous cells for analysis of drug metabolism and drug-drug interactionsBiochemical Pharmacology, 1993
- Terfenadine-Ketoconazole InteractionJAMA, 1993
- The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and NomenclatureDNA and Cell Biology, 1993
- Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycinClinical Pharmacology & Therapeutics, 1992
- Techniques for pharmacological and toxicological studies with isolated hepatocyte suspensionsLife Sciences, 1992
- The UDP Glucuronosyltransferase Gene Super family: Suggested Nomenclature Based on Evolutionary DivergenceDNA and Cell Biology, 1991
- cDNA-expressed human cytochrome P450s: a new age of molecular toxicology and human risk assessmentMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1991
- The Use of Human Liver for Foreign Compound Metabolism and Toxicity StudiesDrug Metabolism Reviews, 1989
- Tissue slicing and culturing revisitedTrends in Pharmacological Sciences, 1987