Active HSF1 Significantly Suppresses Polyglutamine Aggregate Formation in Cellular and Mouse Models
Open Access
- 1 October 2005
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 280 (41) , 34908-34916
- https://doi.org/10.1074/jbc.m506288200
Abstract
No abstract availableKeywords
This publication has 57 references indexed in Scilit:
- Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal deathNature, 2004
- Protein aggregation and neurodegenerative diseaseNature Medicine, 2004
- Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseasesNature, 2002
- Chaperones Hsp70 and Hsp40 Suppress Aggregate Formation and Apoptosis in Cultured Neuronal Cells Expressing Truncated Androgen Receptor Protein with Expanded Polyglutamine TractJournal of Biological Chemistry, 2000
- Modulation of tolerance by mutant heat shock transcription factorsCell Stress and Chaperones, 1999
- Phosphorylation of αB-crystallin in Mitotic Cells and Identification of Enzymatic Activities Responsible for PhosphorylationJournal of Biological Chemistry, 1998
- Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in BrainScience, 1997
- Oligomerization of Expanded-Polyglutamine Domain Fluorescent Fusion Proteins in Cultured Mammalian CellsBiochemical and Biophysical Research Communications, 1997
- Ultrastructure and immunohistochemistry of the coronary chemoreceptor in human and canine heartsAmerican Heart Journal, 1995
- Cloning of a cDNA for Heat-Shock Protein hsp40, a Human Homolog of Bacterial DnaJBiochemical and Biophysical Research Communications, 1993