HYPOCRELLIN‐A SENSITIZED PHOTOOXIDATION OF BILIRUBIN
- 1 December 1989
- journal article
- research article
- Published by Wiley in Photochemistry and Photobiology
- Vol. 50 (6) , 827-830
- https://doi.org/10.1111/j.1751-1097.1989.tb02914.x
Abstract
Abstract— Hypocrellin A (HA) extracted from Hypocrellia batnbusae (b.et Br.) sace, a derivative of 3,10‐dihydroxy‐4,9‐perylenequinone, is a highly effective photosensitizer. Kinetic studies of the HA‐sensitized photooxidation of bilirubin IXα (BR) in different solvents in the presence of various active oxygen quenchers indicate that in aprotic solvents the photooxidation goes via a Type II (1O2) mechanism, whereas in alkaline protic solvents Type I (electron transfer from an excited state of HA to the ground state of oxygen or the BR substrate). Type II and probably free radical reactions may occur simultaneously.This publication has 8 references indexed in Scilit:
- Bilirubin Is an Antioxidant of Possible Physiological ImportanceScience, 1987
- `Like a Shrivelled Blood Orange'—Bilirubin, Jaundice, and PhototherapyPediatrics, 1985
- Interception of O2− by benzoquinone in cyanoaromatic-sensitized photooxygenationsTetrahedron Letters, 1984
- Molecular mechanisms of phototherapy for neonatal jaundiceAccounts of Chemical Research, 1984
- Bilirubin Photooxidation Products in the Urine of Jaundiced Neonates Receiving PhototherapyPediatric Research, 1984
- Die Struktur des Hypocrellins und seines Photooxidationsproduktes PeroxyhypocrellinEuropean Journal of Organic Chemistry, 1981
- THE PHOTOREACTIVITY OF BILIRUBIN AND RELATED PYRROLESPhotochemistry and Photobiology, 1977
- p-Nitrosodimethylaniline as an OH Radical Scavenger in Radiation Chemistry1Journal of the American Chemical Society, 1965