Prostatic Serum Acid Phosphatase in Patients With Localized Prostatic Cancer
- 1 February 1956
- journal article
- research article
- Published by Oxford University Press (OUP) in American Journal of Clinical Pathology
- Vol. 26 (2) , 120-130
- https://doi.org/10.1093/ajcp/26.2.120
Abstract
Total serum acid phosphatase (SAP) and prostatic SAP were measured simultaneously in 20 men having localized untreated prostatic cancer. Prostatic SAP was that part of total SAP inhibited by tartrate. Phosphatase was determined by 2 methods, i.e. using p-nitrophenyl phosphate and disodium phenyl phosphate as substrates, respectively. With the former, 4 men had elevated total SAP and 7 had elevated prostatic SAP. With both methods, only 1 patient had elevated prostatic and normal total SAP. Prostatic SAP measurements seemed a more sensitive indication of liberation of prostatic secretion into the blood than total SAP but were not superior to total SAP determinations in diagnosis of untreated localized prostatic cancer.Keywords
This publication has 1 reference indexed in Scilit:
- A Method for Estimating Serum Acid Phosphatase of Prostatic OriginJournal of Biological Chemistry, 1953