SCOP: a Structural Classification of Proteins database
Open Access
- 1 January 1999
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 27 (1) , 254-256
- https://doi.org/10.1093/nar/27.1.254
Abstract
The Structural Classification of Proteins (SCOP) database provides a detailed and comprehensive description of the relationships of all known proteins structures. The classification is on hierarchical levels: the first two levels, family and superfamily, describe near and far evolutionary relationships; the third, fold, describes geometrical relationships. The distinction between evolutionary relationships and those that arise from the physics and chemistry of proteins is a feature that is unique to this database, so far. The database can be used as a source of data to calibrate sequence search algorithms and for the generation of population statistics on protein structures. The database and its associated files are freely accessible from a number of WWW sites mirrored from URL http://scop.mrc-lmb.cam.ac.uk/scop/Keywords
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