POTENCY OF KILLED PLAGUE VACCINES PREPARED FROM AVIRULENT YERSINIA-PESTIS

  • 1 January 1980
    • journal article
    • research article
    • Vol. 58  (5) , 753-756
Abstract
Killed plague vaccines prepared from avirulent strains A1122 and EV76S of Y. pestis were more effective in mouse potency tests than samples of Plague Vaccine, USP, prepared from killed Y. pestis of the virulent strain 195/P. Manufacture of vaccine from avirulent Y. pestis would obviate requirements for the large containment facilities that are currently needed for producing Plague Vaccine, USP.