Clinical Comparison of Full-Field Digital Mammography and Screen-Film Mammography for Detection of Breast Cancer

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Abstract
OBJECTIVE. The purpose of this work is to compare full-field digital mammography and screen-film mammography for the detection of breast cancer in a screening population.SUBJECTS AND METHODS. Full-field digital mammography was performed in addition to screen-film mammography in 6736 examinations of women 40 years old and older presenting for screening mammography at either of two institutions. Two views of each breast were acquired with each technique. The digital and screen-film mammograms were each interpreted independently. In addition to a clinical assessment, each finding was assigned a probability of malignancy for use in receiver operating characteristic analysis. In cases in which the digital and screen-film interpretations differed, a side-by-side analysis was performed to determine the reasons for the discrepancy. With few exceptions, findings detected on either technique were evaluated with additional imaging and, if warranted, biopsy.RESULTS. Additional evaluation was recommended on at least o...