Abstract
N-Methylglutamate dehydrogenase, purified to a specific activity of 0.29 U/mg of protein, gave 1 band on sodium dodecyl sulfate/polyacrylamide-gel electrophoresis, corresponding to a MW of 130,000. Enzyme-Triton complexes had a partial specific volume of 0.73 cm3/g suggesting that the protein binds < 0.1 g of Triton/g of protein. A MW for the intact enzyme in the presence of 1% (wt/vol) Triton X-100 of 550,000 suggested that the enzyme may be a tetramer.