Affinity of the antiviral enantiomers of oxathiolane cytosine nucleosides for human 2′-deoxycytidine kinase
- 6 April 1993
- journal article
- research article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 45 (7) , 1540-1543
- https://doi.org/10.1016/0006-2952(93)90058-5
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosineAntimicrobial Agents and Chemotherapy, 1992
- Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosineAntimicrobial Agents and Chemotherapy, 1992
- Enzyme-mediated enantioselective preparation of pure enantiomers of the antiviral agent 2',3'-dideoxy-5-fluoro-3'-thiacytidine (FTC) and related compoundsThe Journal of Organic Chemistry, 1992
- Deoxycytidine deaminase-resistant stereoisomer is the active form of (+/-)-2',3'-dideoxy-3'-thiacytidine in the inhibition of hepatitis B virus replication.Published by Elsevier ,1992
- Insights Into HIV Chemotherapy*AIDS Research and Human Retroviruses, 1992
- (-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitroAntimicrobial Agents and Chemotherapy, 1992
- Synthesis of enantiomerically pure (2'R,5'S)-(-)-1-(2-hydroxymethyloxathiolan-5-yl)cytosine as a potent antiviral agent against hepatitis B virus (HBV) and human immunodeficiency virus (HIV)The Journal of Organic Chemistry, 1992
- Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytesAntimicrobial Agents and Chemotherapy, 1992
- The separated enantiomers of 2'-deoxy-3'-thiacytidine (BCH 189) both inhibit human immunodeficiency virus replication in vitroAntimicrobial Agents and Chemotherapy, 1992
- Anti-human immunodeficiency virus type 1 activity and in vitro toxicity of 2'-deoxy-3'-thiacytidine (BCH-189), a novel heterocyclic nucleoside analogAntimicrobial Agents and Chemotherapy, 1991