Differences in Tolerance to Intravenous Xylocaine® and Citanest®

Abstract
SUMMARY: In a study of the tolerance to intravenous injections of two equipotent local anesthetics, Xylocaine and Citanest, in man, marked differences in subjective and objective symptoms have been recorded. No significant circulatory response was recorded and the EEG was also without significant change. A statement is made that Citanest is twice as well tolerated as Xylocaine in intravenous injection and the justification of this statement is discussed.