A New Protecting Group for Phenols: Phenylthiomethyl (PTM) Ethers
- 1 January 1980
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 10 (12) , 911-914
- https://doi.org/10.1080/00397918008061850
Abstract
Hemithioacetals have previously found utility as protecting groups for alcohols and phenols. In particular, the protection of alcohols2,3,4 and phenols5 as methylthiomethyl (MTM) ethers, and the facile hydrolysis of these ethers back to the parent alcohol or phenol have been reported. We now wish to report the use of phenylthiomethyl (PTM) ethers as phenolic protecting groups which may be differentiated from phenolic MTM ethers.Keywords
This publication has 4 references indexed in Scilit:
- Protection of phenols as methylthiomethyl ethersTetrahedron Letters, 1977
- Methylthiomethyl ethers : general synthesis and mild cleavage. Protection of hydroxyl groupsTetrahedron Letters, 1976
- Protection of tertiary hydroxyl groups as methylthiomethyl ethersTetrahedron Letters, 1976
- Protection of primary hydroxyl groups as methylthiomethyl ethersTetrahedron Letters, 1975