Non‐Hodgkin malignant lymphomas and Hodgkin's disease in first‐degree relatives

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Abstract
The occurrence of malignant lymphomas in 3 siblings is described. The cases include the first report of Hodgkin''s disease and non-Hodgkin malignant lymphoma in dizygotic twins. Another remarkable feature was the development of malignant lymphoma, when the siblings were at the same age. Although a transmissible agent or environmental factors cannot be excluded in this family, our observations may suggest a mutual genetic predisposition in Hodgkin''s disease and non-Hodgkin malignant lymphoma.