It has been recognized for some time that arsphenamin could, when given intravenously, cause arsenical poisoning. At the base hospital at Camp Jackson, there have occurred four cases within the past five months. The most typical of these—a fatal one—is here reported. This fatal result followed the intravenous administration of 0.8 gm. of arsphenamin. The case, in its general features, bears the stamp of arsenical intoxication. The clinical diagnosis was confirmed by abundant laboratory data. REPORT OF CASE J. C., a private, aged 27, in a routine examination of his company gave a positive Wassermann reaction. He had at that time no symptom or sign of syphilis, and denied any venereal history. His physical condition was excellent. An injection of 0.4 gm. of arsphenamin was given intravenously. The reaction following this was so marked that he was kept a week in the hospital. He was then sent to duty, although