Formation of GABA via oxidative deamination of putrescine in ovaries of immature rats after gonadotrophin stimulation

Abstract
The diamine oxidase catalyzed metabolism of14C-putrescine was studied in the ovaries of immature rats with and without stimulation by gonadotrophin. This stimulation resulted in a statistically significant increase in the deamination rate of putrescine with a very predominant production of γ-aminobutyric acid. No formation of polyamines was observed which indicated an importance of putrescine or of products of its oxidative deamination during this cellular activity.

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