Plasma soluble fibrin monomer complexes in the development of diabetic retinopathy.

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Abstract
To elucidate the relationship between plasma soluble fibrin monomer complexes (SFMC) and retinal or vitreous hemorrhages, 11 diabetics were studied for 15 mo. The levels of SFMC in 3 of the 11 cases were elevated prior to hemorrhages and in the other 8 cases SFMC levels were elevated after hemorrhages. There was no significant difference between the fibrinogen (Fbg) concentration before and after hemorrhages. The plasma glucose levels did not change significantly during the observation. Apparently, the SFMC level was not only an indicator of the intracapillary generation of thrombin but an important factor affecting the development of diabetic retinopathy.

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