Myopathy and hypersensitivity to phenytoin
- 1 June 1983
- journal article
- case report
- Published by Wolters Kluwer Health in Neurology
- Vol. 33 (6) , 790
- https://doi.org/10.1212/wnl.33.6.790
Abstract
A 19-year-old man with a generalized seizure disorder was treated with phenytoin. A hypersensitivity reaction was marked by hepatitis, severe myalgia, proximal arm weakness, and high serum creatine kinase. Biopsy was diagnostic of myopathy. Patients demonstrating abnormalities of immune responsiveness may best be managed by use of an alternative anticonvulsant.Keywords
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