Toxicological Findings in a Fatal Case of Acebutolol Self-Poisoning
- 1 November 1992
- journal article
- case report
- Published by Oxford University Press (OUP) in Journal of Analytical Toxicology
- Vol. 16 (6) , 398-400
- https://doi.org/10.1093/jat/16.6.398
Abstract
A fatal case of acebutolol self-poisoning is presented. After single-step liquid-liquid alkaline extraction, acebutolol was identified by using an HPLC/DAD screening procedure. By means of a specific HPLC method, acebutolol was then quantified in a large range of postmortem samples. The blood acebutolol concentration was 34.7 µg/mL. The tissue distribution of the drug is discussed in the light of the existing literature.Keywords
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