Nonspecific Esterase Activity in ‘Hairy Cells’
- 1 January 1977
- journal article
- research article
- Published by S. Karger AG in Acta Haematologica
- Vol. 58 (2) , 103-107
- https://doi.org/10.1159/000207815
Abstract
Nonspecific esterase activity using .alpha.-naphthyl butyrate as substrate was present in hairy cells from patients with hairy cell leukemia. Activity of this enzyme was markedly diminished and in some instances obliterated by sodium fluoride. Since .alpha.-naphthyl butyrate is believed to be a more specific substrate for monocytic-type nonspecific esterase than .alpha.-naphthyl acetate, its presence in hairy cells combined with fluoride inhibition which is also characteristic of monocytic nonspecific esterase provides additional evidence of monocytic properties of hairy cells.This publication has 1 reference indexed in Scilit:
- A Study of the Nature of “Hairy” Cells, with Emphasis on Enzymatic MarkersAmerican Journal of Clinical Pathology, 1976