A plasmid-encoded VEGF siRNA reduces glioblastoma angiogenesis and its combination with interleukin-4 blocks tumor growth in a xenograft mouse model

Abstract
Angiogenesis is required for the development and biologic progression of glioblastoma multiforme (GBM), which is the most malignant infiltrative astrocytoma. Vascular endothelial growth factor (VEG...

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