Hodgkin's disease in Western India review of 1082 cases

Abstract
Hodgkins''s disease (HD) had a low overall incidence rate in Bombay when compared to western countries. However, the incidence rate in childhood was quite high. Review of 1082 cases of Hodgkin''s disease recorded at the Tata Memorial Hospital, Bombay, India during a period of 35 yr showed that mixed cellularity, with 54% of the total, was the most frequent histologic subtype and this, together with lymphocyte depleted type formed 68% of all HD. The nodular sclerosis type formed only 9%. A bimodal character of the age pattern with a young age peak in the 2nd decade of life, a male preponderance, a high incidence in childhood, and the predominance of the low survival types, are the major features of the disease in India. The current data, which are the largest series reported from Bombay and other parts of India, indicate that the type-I pattern may be the characteristic feature of the Hodgkin''s disease in India.

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