Salicylate Ototoxicity

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Abstract
IT is known that large doses of salicylates produce deafness, tinnitus and vertigo. These symptoms are often used to titrate the dosage of this medication necessary to relieve the pain of severe arthritis. Their reversibility makes such a program possible.The concept that these symptoms are dose related and reversible is not well documented in the literature of otology or rheumatology. There is, in fact, no report indicating the severity or nature of the hearing loss attributable to this drug. Moreover, blood salicylate levels have never been correlated with audiometric studies in acute salicylate intoxication.The present report represents a . . .

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