Copper Reagents: A New and Efficient Solution for the Selective Addition of Metallated Propargylic Amines to Aldehydes
- 17 June 2003
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 5 (14) , 2567-2569
- https://doi.org/10.1021/ol034893m
Abstract
Anti α-amino-homopropargylic alcohols are prepared by addition of metallated propargylic amines to aldehydes. Among the four organometallic (LI, Zn, Ti, Cu) derivatives used, the most effective are the copper reagents.Keywords
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