CXC Chemokines: Angiogenesis, Immunoangiostasis, and Metastases in Lung Cancer
- 1 December 2004
- journal article
- review article
- Published by Wiley in Annals of the New York Academy of Sciences
- Vol. 1028 (1) , 351-360
- https://doi.org/10.1196/annals.1322.041
Abstract
Abstract: CXC chemokines have been found to be important in the regulation of angiogenesis and tumor‐related immunity, and in promoting organ‐specific metastases. This review highlights the importance of CXC chemokine ligands and receptors in mediating non‐small cell lung cancer tumor‐associated angiogenesis, “immunoangiostasis,” and organ‐specific metastases. These findings may ultimately lead to clinical strategies to target CXC chemokines in non‐small cell lung cancer.Keywords
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