Mechanism of the mutagenic action of hydroxylamine. IX. The UV-induced cleavage of the N-O bond in N4-hydroxy-and N4-methoxycytidine and N6-methoxyadenosine
Open Access
- 1 December 1975
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 2 (12) , 2269-2278
- https://doi.org/10.1093/nar/2.12.2269
Abstract
The principal UV-induced (λ = 254 nm) reaction of N4 - hydroxy- and N4 methoxycytidines and N6 -methoxyadenosine in neutral aqueous solutions is cleavage of the exocyclic N-O bond with the respective formation of citidine and adenosine. Quantum yields are 2.8×10−3 and 2.2×10−3 M/E for the first two compounds and 9.1×10−3 M/E for N6-methoxyadenosine.Keywords
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