DC-ATLAS: a systems biology resource to dissect receptor specific signal transduction in dendritic cells
Open Access
- 1 January 2010
- journal article
- Published by Springer Nature in Immunome Research
- Vol. 6 (1) , 10
- https://doi.org/10.1186/1745-7580-6-10
Abstract
The advent of Systems Biology has been accompanied by the blooming of pathway databases. Currently pathways are defined generically with respect to the organ or cell type where a reaction takes place. The cell type specificity of the reactions is the foundation of immunological research, and capturing this specificity is of paramount importance when using pathway-based analyses to decipher complex immunological datasets. Here, we present DC-ATLAS, a novel and versatile resource for the interpretation of high-throughput data generated perturbing the signaling network of dendritic cells (DCs).Keywords
This publication has 40 references indexed in Scilit:
- Pattern Recognition Receptors and InflammationCell, 2010
- Inhibition of TLR3 and TLR4 function and expression in human dendritic cells by helminth parasitesBlood, 2008
- LPS/TLR4 signal transduction pathwayCytokine, 2008
- Toll-Like Receptors (TLRs) and Their LigandsPublished by Springer Nature ,2008
- Prostaglandin E2 is a key factor for monocyte-derived dendritic cell maturation: enhanced T cell stimulatory capacity despite IDOJournal of Leukocyte Biology, 2007
- nuID: a universal naming scheme of oligonucleotides for Illumina, Affymetrix, and other microarraysBiology Direct, 2007
- 1-Methyl-Tryptophan Can Interfere with TLR Signaling in Dendritic Cells Independently of IDO ActivityThe Journal of Immunology, 2006
- Oxidized Phospholipids Negatively Regulate Dendritic Cell Maturation Induced by TLRs and CD40The Journal of Immunology, 2005
- Dendritic cell immunotherapy: mapping the wayNature Medicine, 2004
- An Approximately Unbiased Test of Phylogenetic Tree SelectionSystematic Biology, 2002