Substituent effects in chemical carcinogenesis: Methyl derivatives of the benzacridines
- 1 April 1979
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 16 (3) , 421-425
- https://doi.org/10.1002/jhet.5570160302
Abstract
An explanation for the different carcinogenic potencies observed among methyl derivatives of the angular benzacridines is given in terms of the tendencies of these compounds to undergo specific metabolic activating reactions analogous to those of polycyclic aromatic hydrocarbons. Theoretical reactivity indices representing these reactions correlate with the carcinogenic activities of these compounds.This publication has 11 references indexed in Scilit:
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