THE SIGNIFICANCE OF WORK LOAD AND INJECTED VOLUME IN XENON133MEASUREMENT OF MUSCULAR BLOOD FLOW

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Abstract
Measuring peak flow in the anterior tibial muscle with radioactive xenon in normal and diabetic persons, it was shown that the same results were obtained during ischaemia both after one minute of work and after maximal work.There was no difference when the peak flow was measured after the injection of 0.05 and 0.2 ml of the solution of radioactive xenon.The coefficient of variation in repeated experiments was 18% for the peak flow and 30% for the latency time.In a group of non‐diabetics (age range between 20 and 49 years) the resting flow was 1.6 ml per 100 g per min ± 0.8. The peak flow after maximal work during ischaemia was 71 ml per 100 g per min ± 18. The mean latency time was 0.47 min ± 0.18.