Modification of spontaneous and hormone-induced sexual behavior by estrogen administered to neonatal female rats.

1 January 1965

journal article
Published by American Psychological Association (APA) in Journal of Comparative and Physiological Psychology

Vol. 60 (1) , 150-152
https://doi.org/10.1037/h0022300

Abstract

31 female rats were administered either estradiol benzoate or peanut oil 96 hr. after birth. As adults 2 of the 23 estrogen-treated rats and 7 of the 8 oil-treated rats ovulated. The estrogen-treated females did not exhibit normal lordosis responses when mated, even though vaginal cyclicity was present, and none became pregnant. All oil-treated females became pregnant. When castrated and given estrogen and progesterone, the oil-treated females displayed lordosis when mounted, whereas typical lordosis was rarely observed in the estrogen-treated females. (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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