The Syntheses of (R)-(+)-b-Vanillyl-g-butyrolactone and of Chiral Lignans Therefrom
- 1 January 1987
- journal article
- research article
- Published by CLOCKSS Archive in HETEROCYCLES
- Vol. 26 (5) , 1169-1172
- https://doi.org/10.3987/r-1987-05-1169
Abstract
-(R)-(+)-.beta.-vanillyl-.gamma.-butyrolactone was obtained in 4 steps including a resolution, from vanillin and dimethyl succinate, and was used for the total synthesis of 5 naturally occurring and optically active lignans such as (+)-isolariciresinol 20.Keywords
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