Measurement of cardiac output by thermal-dilution and direct Fick methods in dogs.

Abstract
This present work is an assessment of a catheter tip thermal-dilution method for cardiac output determination in comparison with the direct Fick method. A high-frequency electric heater on a bilumen cardiac catheter is used to introduce heat at a predetermined constant rate into the blood flowing through the right atrium and superior vena cava. After temperature uniformity of the mixed venous blood is reached by the pumping action of the right ventricle, a temperature transducer on the distal segment of the catheter measures the mean temperature rise in the pulmonary artery, which ranges from 0.04 to 0.1 C. Cardiac output is inversely proportional to the temperature rise and is independent of the cross-sectional area of the pulmonary artery. This method and the direct Fick method have been applied to 11 dogs. The repeated, simultaneous measurements obtained by these 2 methods showed close correlation.

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