NMR INVITRO MEASUREMENTS - A QUALITY-CONTROL STUDY OF THE RADX TABLE-TOP SPECTROMETER

  • 1 January 1985
    • journal article
    • research article
    • Vol. 17  (1) , 123-129
Abstract
A series of experiments was performed to evaluate the accuracy and reproducibility of relaxation values obtained by 2 RADX table-top spectrometers operating at 5 MHz (R5) and 10 MHz (R10), respectively. The output (T1 [spin-lattice relaxation time], T2 [spin-spin relaxation time] and protein content) of each machine was compared (for tissue specimens and paragmagnetic solutions) to reference spectrometers. In the range of tissue T1''s, R5 overestimates T1 by .apprx. 10% and R10 underestimates by .apprx. 23%. For tissue specimens, the T2 output of both machines is within 3% of the reference facility. Proton content values correlate well with the % wet wt of tissues (y = 0.46x + 24, r = 0.85), but accuracy deteriorates badly if tissue T2 > 400 ms of T1 > 300 ms. The output of both machines in accurate and reproducible within 5% over the range of tissue relaxation values (biological fluids excluded).