Failure to detect papovavirus-associated T antigens in human brain tumor cells by anticomplement immunofluorescence
- 1 March 1980
- journal article
- research article
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 52 (3) , 367-370
- https://doi.org/10.3171/jns.1980.52.3.0367
Abstract
To probe the possible presence of papovavirus-related T [tumor] antigen(s) in human brain tumors, the imprinted or cultured cells at various passage levels were examined by anticomplement immunofluorescence using antisera to T antigen of each BK virus, JC virus and simian virus 40. No T antigen was demonstrated in any tests with cells derived from 69 patients with various brain tumors. Tumor cell strains (22) cultured in the presence of a tumor promoter, phorbol ester, also failed to show the T antigen.This publication has 36 references indexed in Scilit:
- Failure to demonstrate papovavirus tumor antigen in human cerebral neoplasmsAnnals of Neurology, 1978
- Persisting oncogenic herpesvirus induced by the tumour promoter TPANature, 1978
- Microfluorometric analysis of anti-complement and indirect immunofluorescence tests for human papovavirus (JCV and BKV) T antigensInternational Journal of Cancer, 1978
- Characterization of Human Papovavirus RFV: Comparison with SV40 and BKVJournal of General Virology, 1977
- Transformation of rabbit kidney cells by bkv(mm) human papovavirusInternational Journal of Cancer, 1977
- A Comparison of Human Papovavirus T AntigensJournal of General Virology, 1976
- Infectivity, Oncogenicity and Transforming Ability of BK Virus and BK Virus DNAJournal of General Virology, 1976
- Human Papovavirus (JC): Induction of Brain Tumors in HamstersScience, 1973
- Cellular localization of an Epstein‐Barr virus (EBV)‐associated complement‐fixing antigen in producer and non‐producer lymphoblastoid cell linesInternational Journal of Cancer, 1973
- Prevalence in England of Antibody to Human Polyomavirus (B.K.)BMJ, 1973